Design Methods in Synthetic and Engineering Biology

Synthetic and engineering biology seek to generate synthetic biological solutions for applications in biotechnology, modern agriculture, biofuel production, bioremediation, and medical applications, such as tissue engineering and antimicrobial therapies. Especially to tackle the challenges thrown up by global warming will require new solutions, and engineering biology offers some promising opportunities. Some of the models that we are developing will help us to search systematically for solutions to e.g. biofuel production or carbon capture.

Representative Publications

  1. Information Processing by Simple Molecular Motifs and Susceptibility to Noise →
    Mc Mahon, S.S., Lenive, O., Filippi, S., & Stumpf, M.P.H. (2015). Journal of the Royal Society, Interface / the Royal Society, 12(110), 0597.

  2. Designing Attractive Models Via Automated Identification of Chaotic and Oscillatory Dynamical Regimes →
    Silk, D., Barnes, C.P., Kirk, P.D.W., Kirk, P., Toni, T., Rose, A., et al. (2011). Nature Communications, 2, 489.

  3. Bayesian Design of Synthetic Biological Systems →
    Barnes, C.P., Silk, D., Sheng, X., & Stumpf, M.P.H. (2011). Proceedings of the National Academy of Sciences of the United States of America, 108(37), 15190–15195.

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